Molecular Probes

for Quantitative Neurosciences

Center for Biostructural Imaging of Neurodegeneration


Our research focuses on finding molecular tools to study the nano-anatomy of neurons and other biological systems. We develop tailor-made small binders (aptamers & nanobodies) to detect and quantify molecules in living and fixed cells.  For this, we use different nanoscopy techniques like STED, STORM, DNA-PAINT, ExM, and nanoSIMS to determine the molecular localizations and quantities of our proteins of interest with high precision.