Molecular Probes

for Quantitative Neurosciences

Center for Biostructural Imaging of Neurodegeneration


Our research focuses on finding molecular tools to study the nano-anatomy of neurons and other biological systems. We develop tailor made small binders (aptamers & nanobodies) to detect and quantify molecules in living and in fixed cells.  For this we use different nanoscopy techniques like STED, STORM, DNA-PAINT and lately also nanoSIMS to determine with high precision the molecular localizations and quantities of our proteins of interest.